CAC2 Childhood Cancer Community News Digest (May 19-25)

Assorted News from the Last Week:

The National Cancer Institute reports that about 85 percent of children diagnosed with cancer are alive five years after diagnosis. That news is encouraging, but long-term survivor care brings its own challenges. Research on children diagnosed with acute lymphoblastic leukemia (ALL) shows that the longer a patient’s body mass index (BMI) falls within the overweight/obese category during treatment, the greater the risk of relapse and the lower the chance of survival. Influence of genetic biomarkers on cardiac diseases in childhood cancer survivors: a systematic review The FDA has granted regenerative medicine advance therapy (RMAT) designation to BCB-276, an investigational B7-H3 autologous chimeric antigen receptor (CAR) T-cell therapy, for the treatment of diffuse intrinsic pontine glioma (DIPG) developed by BrainChild Bio, Inc. An international group of scientists has identified a key molecular process that drives Diffuse Midline Glioma. Overview of hepatoblastoma that summarizes its epidemiology, mechanisms, diagnosis, and management as well as quality of life.

Higher levels of dihydrolipoyl transacetylase make Group-3 medulloblastomas vulnerable to copper-mediated death.

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in childhood and one that can be particularly difficult to treat in teens and adults. A study of pediatric oncology patients travel to the US for care.
Upcoming Webinars, Online Opportunities, and Meetings:
10th Annual Mark Hill Memorial Golf Outing on June 6th at White Hawk Country Club benefitting Northwest Indiana Cancer Kids Foundation on June 6 in Crown Point, IN.  Click here for more information and to register. The Coalition Against Childhood Cancer will hold its 2025 Annual Summit, hosted by Children’s National Hospital in Washington DC and presented by Day One Biopharmaceuticals. This annual event reflects the CAC2 values and mission by providing top-notch educational programming, designing multiple opportunities for members to connect and engage, and showcasing the ongoing efforts of our members who are working for a future without childhood cancers.  June 15-17.  Register here: CAC2 Annual Summit Registration

MIB Agents FACTOR Osteosarcoma Conference brings together the leading osteosarcoma researchers, clinicians, patient families, osteosarcoma survivors, patients, and bereaved parents to Make it Better (MIB) for those battling this disease. The conference is is Salt Lake City, UT on June 26 – 28 2025.  Click here for more information and to register.

Past Recordings:

CAC2’s May webinar: “Fertility Hope for Childhood Cancer SurvivorsA pre-med student at Creighton University and childhood cancer survivor fears recent threats to cancer research funding.

Take Action:

At CAC2 we are focused on children with cancer, but the issues impacting them are wide ranging and often far bigger than what the childhood cancer community can accomplish on their own.  We align with others— sometimes leading the charge, sometimes following and supporting their efforts. The following post is a Call to Action from the Haystack Project: The Voices of Rare and Ultra Rare (https://haystackproject.org) concerning possible Medicaid cuts: https://www.cac2.org/guest-blog-save-medicaid-materials-to-share-with-your-communities/.

The International Neuroblastoma Risk Group (INRG) Executive Committee are looking for patient advocates to be active members of the committee.  Expression of Interest document.

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